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Schizophrenia affects the ability to think clearly, control emotions, make decisions and relate to others. Having schizophrenia is a lifelong illness involving many complex problems. While it is difficult to estimate the exact prevalence of schizophrenia in the United States, estimates range from 0.25% to 0.64% of American adults. While schizophrenia can occur at any age, the average onset age for men is in their late teens to early 20s, and for women, it is in their late 20s to early 30s. Schizophrenia is rare in children and adults younger than 12 and older than 40. If diagnosed and treated appropriately, you can manage schizophrenia to lead a fulfilling life.